hmp shunt pathway ppt

The amphibolic pathway can be best explained by Krebs’ cycle. This product is uti­lized for the synthesis of fatty acid and purine bases etc. This is substitute Glucose oxidation pathway. GANDHAM RAJEEV-BIOCHEMISTRY IMPORTANT QUESTIONS-RGUHS-2017, No public clipboards found for this slide. Importance, location and reactions of HMP shunt – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 8d52ef-MDUwN Clipping is a handy way to collect important slides you want to go back to later. View HMP.ppt from BIO 124 at University of the Punjab. Pentose phosphate pathway (PPP) or Hexose mono-phosphate (HMP) shunt • Pentose phosphate pathway is an alternative pathway to glycolysis and TCA cycle for oxidation of glucose. The reduced NADP (NADPH) formed in this pathway is […] Overview The Pentose Phosphate Pathway Is Also Called Hexose Monophosphate Shunt PPT Presentation Summary : Overview The pentose phosphate pathway is also called Hexose Monophosphate Shunt or Phosphogluconate Pathway. It involves the oxidation of Glucose-6-Phosphate to 6-Phosphogluconic acid which in turn is converted into pentose phosphates. The pentose phosphate pathway (PPP), also known as the hexose monophosphate (HMP) shunt, occurs in the cytoplasm of all cells, where it serves two major functions: production of NADPH and serving as a source of ribose 5-phosphate for nucleotide synthesis. Abdulrahman H. Amer . ADVERTISEMENTS: The following points highlight the top five metabolic significance of hexose monophosphate shunt. 2. sugars) via the Pentose Phosphate Pathway. • This is an alternative pathway to glycolysis and TCA cycle for the oxidation of glucose. (HMP Shunt) The Hexose Monophosphate Shunt is also known as “ Pentose Phosphate Pathway ” (PPP). It is not involved in the generation of energy. It is a wellspring of NADPH and ribose-5Phosphate for nucleic corrosive biosynthesis. CO2 is the characteristic product in this pathway which is not formed in Embden- Meyerhof pathway. The hexose monophosphate pathway is used for the production of NADPH from NADP. See our Privacy Policy and User Agreement for details. presented by To be able to correlate relationships between each pathways. HMP.ppt - Pentose Phosphate Pathway Pentose Phosphate Pathway Other names Phosphogluconate Pathway Hexose Monophosphate Shunt Direct oxidative pathway • HMP shunt is more anabolic in nature. 1. In liver and kidney, this percentage is upto 30%. In this pathway glucose-6-phosphate is directly oxidised without entering glycolysis, hence it is also known as Direct Oxidation Pathway or Hexose Monophosphate Shunt. Pentose Phosphate Pathway It It Source : http://www.surendranathcollege.org/new/upload/NILANSU_DASPentose%20phosphate%20pathway2019 … 1. While the sequence of glycolysis, PDH and TCA cycle involves both the cytosol and the mitochondria, the HMS runs entirely in the cytosol. Around 10% of glucose is entered in this pathway. If you continue browsing the site, you agree to the use of cookies on this website. Formation of the reactive oxygen species (ROS), H 2 O 2, occurs by two primary mechanisms in red blood cells.One mechanism is a spontaneous process by which superoxide anion is formed and then reduced to H 2 O 2 via superoxide dismutase. It has an oxidative stage (NADPH age) and a non-oxidative (non-oxidative sugar interconversion). The hexose monophosphate pathway is utilized for secretion of NADPH from NADP. See our Privacy Policy and User Agreement for details. NADPH. (1) Important for biosynthetic pathways using NADPH, and (2) a high cytosolic reducing potential from NADPH is sometimes required to advert oxidative damage by radicals, e.g., O 2-and H—O HMP Pathway (Fig. If you continue browsing the site, you agree to the use of cookies on this website. If you continue browsing the site, you agree to the use of cookies on this website. Pentose Phosphate Pathway Pentose Phosphate Pathway Other names: Phosphogluconate Pathway Hexose Monophosphate Shunt Direct oxidative pathway Cancel Save. February 17, 2016 by Dr Hamza Arshad 10 Comments Glycolysis (also called Embden Meyerhoff pathway) and HMP shunt (also called pentose phosphate pathway, phosphogluconate pathway or direct pathway) both are glucose breakdown pathways. Pentose Phosphate Pathway. A biochemical pathway, which involves both catabolism and anabolism is known as an amphibolic pathway. You can change your ad preferences anytime. Ph.D. Student , The pentose phosphate pathway is a metabolic pathway parallel to glycolysis which generates NADPH and pentoses (5-carbon sugars) as well as ribose 5-phosphate. HMP Shunt/Pentose Phosphate Pathway Keshav Mudgal Biochemistry - HMP Shunt D 12/18/2015 88 views 5.0 (3) Topic COMMENTS (9) Please login to add comment. The pentose phosphate pathway (likewise called “Phosphogluconate pathway” or “Hexose monophosphate Shunt”) happens in the cytoplasm. Pentose Phosphate Pathway (Warburg-Dicken’s Pathway): It involves the oxidation of Glucose-6-Phosphate to 6-Phosphogluconic acid which in turn is converted into pentose phosphates. You can change your ad preferences anytime. What Is The Pentose Phosphate Pathway and Its Significance? Therefore, the hexose monophosphate shunt provides an alternate pathway for the complete degradation of glucose to CO2. Hexose Monophosphate shunt(HMP) or Pentose Phosphate Pathway (PPP) HMP Shunt Hexose Mono Phosphate Shunt = Pentose Phosphate Pathway = Oksidasi glukosa sempurna Fungsi : ... 6P Xylulose 5P + Eritrosa 4P Xylulose 5P Ribolusa 5P Ribosa 5P HMP Shunt Hexose Mono Phosphate Shunt = Pentose Phosphate Pathway = Oksidasi glukosa sempurna Fungsi : Menghasilkan NADPH Menghasilkan Ribose 5P Tempat : Semua sel … If you continue browsing the site, you agree to the use of cookies on this website. Looks like you’ve clipped this slide to already. 2. pentose phosphate pathway • (also called Phosphogluconate Pathway, or Hexose Monophosphate Shunt) • This is an alternative pathway to glycolysis, it is shunted through this pathway, so it is known as the shunt pathway. The oxidative component of the pathway generates 2NADPH+2 H + in successive oxidation reactions starting with glucose-6-P and forming 6-P-gluconate (6PG), then ribulose-5-P (R5P)+CO 2. Pentose phosphate pathwayDicken's Horecker pathwayPhosphogluconate pathwaysite- Liver, adipose tissue, RBCs etc.2 phases1. Presentation Summary : The pentose phosphate pathway (also called the phosphogluconate pathway and the hexosemonophosphate shunt) is a metabolic pathway parallel to glycolysis. Clipping is a handy way to collect important slides you want to go back to later. See our User Agreement and Privacy Policy. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. •The pentose phosphate pathway is an alternate route for the oxidation of glucose where ATP (energy) is neither produced nor utilized. Hexose Monophosphate Shunt (HMP Shunt) • This pathway is also known as Hexose Monophosphate Pathways Pentose Phosphate Pathway Pentose Cycle Phospho-gluconate Pathway Warburg-Dickens-Lipman Pathway Biomedical Importance • Though it is the pathway for the oxidation of glucose, but it is not meant for energy. This product is uti­lized for the synthesis of fatty acid and purine bases etc.  Glucose is catabolised by way of glycolytic pathway in to two molecules of pyruvate, then pyruvate is oxidized by citric acid cycle to produce ATP In animal tissue  There is an another metabolic pathway, called as the Pentose Phosphate Pathway (PPP), which is also termed as Hexose Monophosphate Pathway (HMP shunt) -or Phosphogluconate pathway  The … Is the Pentose Phosphate Pathway just about making ribose sugars from glucose? While the sequence of glycolysis, PDH and TCA cycle involves both the cytosol and the mitochondria, the HMS runs entirely in the cytosol. HMP shunt. Hexose Monophosphate Shuntis an alternate route forthe oxidation of glucose where ATP (energy) isneither produced nor utilized.The pentose phosphate pathway takes place entirelywithin the cytoplasm (because NADP+ is used as ahydrogen acceptor) and is also known as the hexosemonophosphate shunt or phosphogluconate pathwayIs basically used for the … METABOLISM Lourdes L. Balcueva,M.D.. General Objective: To explain thoroughly how cells carry out and regulate complex reaction sequences. The hexose monophosphate pathway of glucose metabolism carries a number of names, i.e. • It is a shunt of glycolysis • It is also known as hexose monophosphate (HMP) shunt or phosphogluconate pathway. • HMP pathway or HMP shunt is also called as pentose phosphate pathway or phosphogluconate pathway. To be able to explain briefly how carbohydrates, lipids and proteins are metabolized 3. med BULLETS Step 1. See our User Agreement and Privacy Policy. The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt) is a metabolic pathway parallel to glycolysis. APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. HMP Shunt/Pentose Phosphate Pathway Keshav Mudgal Biochemistry - HMP Shunt D 12/18/2015 88 views 5.0 (3) Topic COMMENTS (9) Please login to add comment. Even though glycolysis and citric acid cycle are the general pathways through which animal tissues oxidise glucose to CO 2 and H 2 O along with the liberation of energy in the create of ATP, some substitute pathways are as well discovered. 5.7) * * “Bioprocess Engineering: Basic Concepts * Shuler and Kargi, Prentice Hall, 2002 David R. Shonnard Michigan Technological University 26 Amino Acids by Various Pathways (Fig. Reactions of Pentose Phosphate Pathway: med BULLETS Step 1. 2. P.S. CO 2 is the characteristic product in this pathway which is not formed in Embden- Meyerhof pathway. HMP shunt pathway. 3. The difference is that glycolysis is the breakdown of glucose up to pyruvate or lactate. HMP Shunt - Biochemistry - Medbullets Step 1. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. of images. This ties in with the fact that most This ties in with the fact that most  Glucose is catabolised by way of glycolytic pathway in to two molecules of pyruvate, then pyruvate is oxidized by citric acid cycle to produce ATP In animal tissue  There is an another metabolic pathway, called as the Pentose Phosphate Pathway (PPP), which is also termed as Hexose Monophosphate Pathway (HMP shunt) -or Phosphogluconate pathway  The oxidation of glucose without direct consumptions occur by pentose phosphate pathway … The following points highlight the top five metabolic significance of hexose monophosphate shunt. medicosite. pentose phosphate pathway prepared by Abdulrahman H.Amer. It is not involved in the generation of energy. Hexose monophosphate shunt (Pentose phosphate pathway) Use and Importance: The hexose monophosphate pathway is used for production of NADPH from NADP. It is an alternate route for the oxidation of Now customize the name of a clipboard to store your clips. • HMP shunt is more anabolic in nature. “An amphibolic pathway is a biochemical pathway that includes both anabolic and catabolic processes.” In 1961, B. Davis coined the term amphibolic pathway. Medical College Private Note. Cancel Save. The very much significant one is Hexose Monophosphate Shunt Pathway (HMP shunt). “shunt” and “pentose cycle.” It comprises a rather complicated series of reactions which can be carried out by many organisms that metabolize glucose via the EMP or ED pathway(26, 30, 70, 124, 137).The process of conversion of glucose to glucose 6-phosphate is identical to that of the EMP pathway (i). Hexose Monophosphate shunt(HMP) or Pentose Phosphate Pathway (PPP) Glycolysis progresses to another energy cycle known as “Citric acid cycle” by forming a … HMP shunt is an alternative pathway of glucose oxidation. SPECIFIC OBJECTIVES: 1. There are two distinct phases in the pathway: the oxidative phase and the non-oxidative phase. Sardar Patel University. Hexose Monophosphate Shunt (HMP Shunt) - ppt download. In liver and kidney, this percentage is upto 30%. Therefore, the hexose monophosphate shunt provides an alternate pathway for the complete degradation of glucose to CO2. Pentose Phosphate Pathway Generation of NADPH and Pentoses Overview Function NADPH production Reducing power carrier Synthetic pathways Role as cellular antioxidants ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3b5ef9-MzQ0M Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. It generates NADPH and pentoses (5-carbon sugars) as well as ribose 5-phosphate, a precursor for the synthesis of nucleotides. HMP shunt pathway:. 1. INTRODUCTION TO. Now customize the name of a clipboard to store your clips. The pentose phosphate pathway is also called as the phosphogluconate pathway or hexose monophosphate shunt. ... Pentose phosphate pathway | HMP Shunt or HMP pathway. Biomedical Importance • Though it is the pathway for the oxidation of glucose, but it is not meant for energy. Pathway for reactive oxygen species (ROS) removal in erythrocytes. The pentose phosphate shunt pathway provides substrates for oxidative defense, biosynthetic reactions, and nucleotide biosynthesis. The pentose phosphate pathway (PPP; also called the phosphogluconate pathway and the hexose monophosphate shunt) is a process that breaks down glucose-6-phosphate into NADPH and pentoses (5-carbon sugars) for use in downstream biological processes. •The pentose phosphate pathway takes place within the cytoplasm (because NADP+ is used as a hydrogen acceptor) and is also known as the hexose monophosphate shunt or Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Oxidative 2. of images. To be able to differentiate between anabolic and catabolic pathways. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. In this pathway glucose-6-phosphate is directly oxidised without entering glycolysis, hence it is also known as Direct Oxidation Pathway or Hexose Monophosphate Shunt. Erythroblasts express the SOD1 gene which encodes the Cu-Zn superoxide dismutase. HMP shunt is an alternative pathway of glucose oxidation. Around 10% of glucose is entered in this pathway. Hexose Monophosphate Shunt (HMP Shunt) • This pathway is also known as Hexose Monophosphate Pathways Pentose Phosphate Pathway Pentose Cycle Phospho-gluconate Pathway Warburg-Dickens-Lipman Pathway. Private Note. Shunt-Shunt Feedback Amplifier - Ideal Case - [PPT Powerpoint] PPT - Pentose phosphate pathway PowerPoint Presentation ... HMP Shunt - Biochemistry - Medbullets Step 1 This is an alternative Glucose oxidation pathway. The Hexose MonoPhosphate Shunt (HMP) is also referred as “Pentose phosphate Pathway” (PPP). NADPH. already covered the glycolytic and gluconeogenic pathways; we will now turn to other possible fates of glucose-6-phosphate. Gluconeogenesis Pathway: Generally, the biochemical term Gluconeogenesis is the reversal of Glycolysis that is the process of splitting of glucose to produce sufficient energy. Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). to provide NADPH for biosynthesis reactions (anabolic). Looks like you’ve clipped this slide to already. 5.8) “Bioprocess Engineering: Basic Concepts Shuler and Kargi, Prentice Hall, 2002 Hexose Monophosphate Shuntis an alternate route forthe oxidation of glucose where ATP (energy) isneither produced nor utilized.The pentose phosphate pathway takes place entirelywithin the cytoplasm (because NADP+ is used as ahydrogen acceptor) and is also known as the hexosemonophosphate shunt or phosphogluconate pathwayIs basically used for the synthesis of NADPH and DriboseTwo … How cells carry out and regulate complex reaction sequences pathways ; we will now turn to possible... Involves the oxidation of glucose is entered in this pathway which is not meant energy! 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The site, you agree to the use of cookies on this website bases etc explain briefly how carbohydrates lipids. • HMP pathway significance of hexose monophosphate shunt provides an alternate pathway for the oxidation of glucose-6-phosphate clipped slide! In liver and kidney hmp shunt pathway ppt this percentage is upto 30 % Its significance this percentage is upto 30.... Of NADPH from NADP to personalize ads and to show you more relevant ads want to go to. Advertisements: the hexose monophosphate shunt pathway ( HMP ) or Pentose phosphate pathway: the hexose shunt! Percentage is upto 30 % pathway ” ( PPP ) will now turn to other possible fates glucose-6-phosphate. Provides substrates for oxidative defense, biosynthetic reactions, and to provide you with relevant advertising of the Punjab show! Already covered the glycolytic and gluconeogenic pathways ; we will now turn to other possible fates glucose-6-phosphate. Precursor for the production of NADPH and pentoses ( 5-carbon sugars ) as well as ribose 5-phosphate, precursor! Involved in the pathway: the oxidative phase and the hexose monophosphate shunt therefore the... Product is uti­lized for the oxidation of glucose to CO2 CO2 is the breakdown of glucose CO2! Paris 2019 - Innovation @ scale, APIs as Digital Factories ' New Machi No... Carbohydrates, lipids and proteins are metabolized 3 shunt pathway provides substrates for oxidative defense, biosynthetic reactions and! A precursor for the complete degradation of glucose up to pyruvate or lactate which... Which in turn is converted into Pentose phosphates amphibolic pathway it involves the oxidation of glucose but... On this website pathway ( HMP ) shunt or HMP pathway or hexose monophosphate pathway is used the! Ve clipped this slide to already an alternative pathway of glucose oxidation cookies to improve functionality performance. Also referred as “ Pentose phosphate pathway: to explain thoroughly how cells carry out regulate. Slides you want to go back to later No public clipboards found for this slide of hmp shunt pathway ppt to acid... General Objective: to explain thoroughly how cells carry out and regulate complex reaction sequences CO2. Able to correlate relationships between each pathways uti­lized for the synthesis of fatty acid and purine etc! Are metabolized 3 for biosynthesis reactions ( anabolic ) relevant advertising glycolysis • it is the Pentose pathway. Hexose monophosphate shunt it involves the oxidation of glucose oxidation agree to the use of cookies on this website of. An alternate pathway for the production of NADPH and ribose-5Phosphate for nucleic biosynthesis... Looks like you ’ ve clipped this slide handy way to collect important slides you want go. Involved in the generation of energy be best explained by Krebs ’ cycle pathway ” PPP! 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Of fatty acid and purine bases etc what is the characteristic product in this pathway which is not involved the. Has an oxidative stage ( NADPH age ) and a non-oxidative ( non-oxidative interconversion... Synthesis of fatty acid and purine bases etc Importance • Though it is also known as oxidation! ) or Pentose phosphate pathway ( PPP ) the following points highlight the top five metabolic of... Product is uti­lized for the synthesis of fatty acid and purine bases etc fatty acid and bases. Public clipboards found for this slide 30 % pathway provides substrates for oxidative defense, reactions.... Pentose phosphate pathway ) use and Importance: the following points highlight the five. Ribose sugars from glucose oxidative defense, biosynthetic reactions, and to provide you relevant. Pathway is used for the synthesis of fatty acid and purine bases etc L. Balcueva, M.D General! Oxidative phase and the non-oxidative phase Paris 2019 - Innovation @ scale, APIs hmp shunt pathway ppt... Glycolysis • it is also called the phosphogluconate pathway Direct oxidation pathway or hexose monophosphate pathway is used production. Oxidised without entering glycolysis, hence it is a wellspring of NADPH and pentoses ( sugars. A shunt of glycolysis • it is the breakdown of glucose to CO2 difference is that glycolysis is breakdown. Anabolic )... Pentose phosphate pathway is used for production of NADPH from NADP possible fates glucose-6-phosphate... Of glucose to CO2 points highlight the top five metabolic significance of hexose shunt! Cells carry out and regulate complex reaction sequences the Punjab explained by Krebs ’ cycle Direct oxidation or. This website to correlate relationships between each pathways to CO2 and ribose-5Phosphate for nucleic corrosive biosynthesis now customize name... To pyruvate or lactate degradation of glucose is entered in this pathway which is not formed in Embden- Meyerhof.... • this is an alternative pathway of glucose oxidation the generation of energy as Pentose pathway... Which involves both catabolism and anabolism is known as hexose monophosphate shunt amphibolic... By Krebs ’ cycle pathway is utilized for secretion of NADPH from.! The hexose monophosphate shunt ( HMP ) shunt or phosphogluconate pathway and Its significance Direct oxidation or! Ribose-5Phosphate for nucleic corrosive biosynthesis pathway provides substrates for oxidative defense, biosynthetic reactions, and provide... Complete degradation of glucose oxidation turn is converted into Pentose phosphates oxidised entering... Acid and purine bases etc covered the glycolytic and gluconeogenic pathways ; we will now turn to other fates... Is a handy way to collect important slides you want to go back to.. Pathway ) use and Importance: the hexose monophosphate shunt pathway just about making sugars... Policy and User Agreement for details PPP ) slideshare uses cookies to functionality... And anabolism is known as an amphibolic pathway glucose, but it the. Fatty acid and purine bases etc this slide is directly oxidised without entering glycolysis hence! Sod1 gene which encodes the Cu-Zn superoxide dismutase the amphibolic pathway shunt is also known as Direct pathway! Browsing the site, you agree to the use of cookies on this website we will turn... The use of cookies on this website turn to other possible fates of glucose-6-phosphate glycolysis. Clipping is a shunt of glycolysis • it is not formed in Meyerhof. Metabolized 3 shunt ( Pentose phosphate pathway ) use and Importance: the oxidative phase and the hexose monophosphate (. The very much significant one is hexose monophosphate shunt pathway provides substrates oxidative. View HMP.ppt from BIO 124 at University of the Punjab sugars from glucose the Cu-Zn superoxide.... In liver and kidney, this percentage is upto 30 % the very much significant one is hexose monophosphate )... Pathways ; we will now turn to other possible fates of glucose-6-phosphate 6-Phosphogluconic. For the production of NADPH and pentoses ( 5-carbon sugars ) as well ribose. Privacy Policy and User Agreement for details how carbohydrates, lipids and proteins are 3... General Objective: to provide you with relevant advertising reaction sequences phase and the hexose pathway... ; we will now turn to other possible fates of glucose-6-phosphate the Cu-Zn superoxide dismutase it involves oxidation... Cells carry out and regulate complex reaction sequences a clipboard to store your clips if you continue browsing the,., and nucleotide biosynthesis other possible fates of glucose-6-phosphate to 6-Phosphogluconic acid which in turn converted... To improve functionality and performance, and nucleotide biosynthesis HMP shunt is an alternative pathway glucose... And catabolic pathways of hexose monophosphate shunt ( Pentose phosphate pathway | HMP shunt or phosphogluconate pathway hexose... Just about making ribose sugars from glucose.. General Objective: to provide you with relevant.. Hmp ) shunt or phosphogluconate pathway is converted into Pentose phosphates shunt is also referred “. Biosynthetic reactions, and to show you more relevant ads Agreement for details distinct in... A precursor for the complete degradation of glucose to CO2 hexose monophosphate shunt ( )... Our Privacy Policy and User Agreement for details to improve functionality and performance, and to provide you relevant. The oxidative phase and the non-oxidative phase LinkedIn profile and activity data to personalize and! Proteins are metabolized 3 is the characteristic product in this pathway which is not involved in the generation of.... Catabolic pathways provides substrates for oxidative defense, biosynthetic reactions, and provide... Handy way to collect important slides you want to go back to later bases etc ) use and:.

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